BDBM50509523 CHEMBL4584937

SMILES: Cc1ccc(cc1NCc1cncc(c1)-c1ccc[nH]1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=YEPVECGOLOSJGA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50509523 (CHEMBL4584937) Show SMILES Cc1ccc(cc1NCc1cncc(c1)-c1ccc[nH]1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C25H21F3N4O/c1-16-7-8-18(24(33)32-21-5-2-4-20(12-21)25(26,27)28)11-23(16)31-14-17-10-19(15-29-13-17)22-6-3-9-30-22/h2-13,15,30-31H,14H2,1H3,(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR2 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...				ACS Med Chem Lett 11: 29-33 (2020) Article DOI: 10.1021/acsmedchemlett.9b00382
					More data for this Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human))	BDBM50509523 (CHEMBL4584937) Show SMILES Cc1ccc(cc1NCc1cncc(c1)-c1ccc[nH]1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C25H21F3N4O/c1-16-7-8-18(24(33)32-21-5-2-4-20(12-21)25(26,27)28)11-23(16)31-14-17-10-19(15-29-13-17)22-6-3-9-30-22/h2-13,15,30-31H,14H2,1H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR1 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...				ACS Med Chem Lett 11: 29-33 (2020) Article DOI: 10.1021/acsmedchemlett.9b00382
					More data for this Ligand-Target Pair