BDBM50510337 CHEMBL4545652
SMILES: Cn1ncc2cccc(-c3ccc(cc3)S(=O)(=O)CC(C)(C)C(=O)N[C@@H](CC(N)=O)C#N)c12
InChI Key: InChIKey=MJZBKUCPUSBGLA-KRWDZBQOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Legumain (Homo sapiens (Human)) | BDBM50510337 (CHEMBL4545652) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University Belfast Curated by ChEMBL | Assay Description Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ... | Bioorg Med Chem Lett 29: 1546-1548 (2019) Article DOI: 10.1016/j.bmcl.2019.03.019 | |||||||||||
More data for this Ligand-Target Pair |