BDBM50510583 CHEMBL4448719

SMILES: COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(Cl)cc4)cc3F)c2cc1OC

InChI Key: InChIKey=SJJBWHOXJKRPHY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510583 (CHEMBL4448719) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(Cl)cc4)cc3F)c2cc1OC Show InChI InChI=1S/C25H21ClFN3O6S/c1-34-23-12-18-20(13-24(23)35-2)28-10-9-21(18)36-22-8-7-17(11-19(22)27)29-25(31)30-37(32,33)14-15-3-5-16(26)6-4-15/h3-13H,14H2,1-2H3,(H2,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair