BDBM50510666 CHEMBL4528746

SMILES: CC[C@](C(C)O)(c1ccc(cc1)C(F)(F)F)n1ncc2c(NS(C)(=O)=O)cccc12

InChI Key: InChIKey=GKBSBEVPPBUZJM-YFKXAPIDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510666   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50510666 (CHEMBL4528746) Show SMILES CC[C@](C(C)O)(c1ccc(cc1)C(F)(F)F)n1ncc2c(NS(C)(=O)=O)cccc12 |r| Show InChI InChI=1S/C20H22F3N3O3S/c1-4-19(13(2)27,14-8-10-15(11-9-14)20(21,22)23)26-18-7-5-6-17(16(18)12-24-26)25-30(3,28)29/h5-13,25,27H,4H2,1-3H3/t13?,19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Antagonist activity at mineralocorticoid receptor (unknown origin)				Bioorg Med Chem Lett 29: 1854-1858 (2019) Article DOI: 10.1016/j.bmcl.2019.04.024
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50510666 (CHEMBL4528746) Show SMILES CC[C@](C(C)O)(c1ccc(cc1)C(F)(F)F)n1ncc2c(NS(C)(=O)=O)cccc12 |r| Show InChI InChI=1S/C20H22F3N3O3S/c1-4-19(13(2)27,14-8-10-15(11-9-14)20(21,22)23)26-18-7-5-6-17(16(18)12-24-26)25-30(3,28)29/h5-13,25,27H,4H2,1-3H3/t13?,19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by gel filtration assay				Bioorg Med Chem Lett 29: 1854-1858 (2019) Article DOI: 10.1016/j.bmcl.2019.04.024
					More data for this Ligand-Target Pair