BDBM50510706 CHEMBL4515068

SMILES: Cc1cc(NNC(N)=S)n2nc(nc2n1)C(F)(F)F

InChI Key: InChIKey=NKFUNWMGDCTBBU-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50510706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase (Leishmania amazonensis)	BDBM50510706 (CHEMBL4515068) Show SMILES Cc1cc(NNC(N)=S)n2nc(nc2n1)C(F)(F)F Show InChI InChI=1S/C8H8F3N7S/c1-3-2-4(15-16-6(12)19)18-7(13-3)14-5(17-18)8(9,10)11/h2,15H,1H3,(H3,12,16,19)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Non-competitive inhibition of Leishmania amazonensis arginase using L-arginine as substrate incubated for 15 mins				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510706 (CHEMBL4515068) Show SMILES Cc1cc(NNC(N)=S)n2nc(nc2n1)C(F)(F)F Show InChI InChI=1S/C8H8F3N7S/c1-3-2-4(15-16-6(12)19)18-7(13-3)14-5(17-18)8(9,10)11/h2,15H,1H3,(H3,12,16,19)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Non-competitive inhibition of Leishmania amazonensis arginase using L-arginine as substrate incubated for 15 mins				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026
					More data for this Ligand-Target Pair
Arginase (Leishmania amazonensis)	BDBM50510706 (CHEMBL4515068) Show SMILES Cc1cc(NNC(N)=S)n2nc(nc2n1)C(F)(F)F Show InChI InChI=1S/C8H8F3N7S/c1-3-2-4(15-16-6(12)19)18-7(13-3)14-5(17-18)8(9,10)11/h2,15H,1H3,(H3,12,16,19)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026
					More data for this Ligand-Target Pair