BDBM50510707 CHEMBL4541649

SMILES: NC(=S)NNc1ncnc2n(ncc12)-c1ccc(cc1)C#N

InChI Key: InChIKey=YCFCSVRBVAWFRQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510707   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase (Leishmania amazonensis)	BDBM50510707 (CHEMBL4541649) Show SMILES NC(=S)NNc1ncnc2n(ncc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C13H10N8S/c14-5-8-1-3-9(4-2-8)21-12-10(6-18-21)11(16-7-17-12)19-20-13(15)22/h1-4,6-7H,(H3,15,20,22)(H,16,17,19)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026
					More data for this Ligand-Target Pair