BDBM50510709 CHEMBL4571367

SMILES: NC(=S)NNc1ncnc2n(ncc12)-c1ccccc1

InChI Key: InChIKey=RVGOKJBWPSYAFH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase (Leishmania amazonensis)	BDBM50510709 (CHEMBL4571367) Show SMILES NC(=S)NNc1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C12H11N7S/c13-12(20)18-17-10-9-6-16-19(11(9)15-7-14-10)8-4-2-1-3-5-8/h1-7H,(H3,13,18,20)(H,14,15,17)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026
					More data for this Ligand-Target Pair