BDBM50510711 CHEMBL4467463

SMILES: NC(=S)NNc1ncnc2n(ncc12)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=ARHQALUONFJBBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510711   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase (Leishmania amazonensis)	BDBM50510711 (CHEMBL4467463) Show SMILES NC(=S)NNc1ncnc2n(ncc12)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H10F3N7S/c14-13(15,16)7-1-3-8(4-2-7)23-11-9(5-20-23)10(18-6-19-11)21-22-12(17)24/h1-6H,(H3,17,22,24)(H,18,19,21)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026
					More data for this Ligand-Target Pair