BDBM50510712 CHEMBL4570250

SMILES: NC(=S)NNc1ncnc2n(ncc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=DSHQBZKBVCOCJM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase (Leishmania amazonensis)	BDBM50510712 (CHEMBL4570250) Show SMILES NC(=S)NNc1ncnc2n(ncc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C12H10ClN7S/c13-7-1-3-8(4-2-7)20-11-9(5-17-20)10(15-6-16-11)18-19-12(14)21/h1-6H,(H3,14,19,21)(H,15,16,18)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Tecnologia em Farmacos Curated by ChEMBL					Assay Description Inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli using L-arginine as substrate				Bioorg Med Chem 27: 3061-3069 (2019) Article DOI: 10.1016/j.bmc.2019.05.026
					More data for this Ligand-Target Pair