BDBM50510714 CHEMBL4526393

SMILES: Fc1ccc(Cn2ccc3c(ncnc23)N2CCC(CC2)N2CCCCC2)cc1

InChI Key: InChIKey=JYDMOJYANAKRDD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510714   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50510714 (CHEMBL4526393) Show SMILES Fc1ccc(Cn2ccc3c(ncnc23)N2CCC(CC2)N2CCCCC2)cc1 Show InChI InChI=1S/C23H28FN5/c24-19-6-4-18(5-7-19)16-29-15-10-21-22(25-17-26-23(21)29)28-13-8-20(9-14-28)27-11-2-1-3-12-27/h4-7,10,15,17,20H,1-3,8-9,11-14,16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK-293 cells incubated for 90 mins by radioligand displace...				Bioorg Med Chem 27: 3194-3200 (2019) Article DOI: 10.1016/j.bmc.2019.05.042
					More data for this Ligand-Target Pair
Histamine receptor (H3 and H4) (Homo sapiens (Human))	BDBM50510714 (CHEMBL4526393) Show SMILES Fc1ccc(Cn2ccc3c(ncnc23)N2CCC(CC2)N2CCCCC2)cc1 Show InChI InChI=1S/C23H28FN5/c24-19-6-4-18(5-7-19)16-29-15-10-21-22(25-17-26-23(21)29)28-13-8-20(9-14-28)27-11-2-1-3-12-27/h4-7,10,15,17,20H,1-3,8-9,11-14,16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cell membranes by radioligand displacement assay				Bioorg Med Chem 27: 3194-3200 (2019) Article DOI: 10.1016/j.bmc.2019.05.042
					More data for this Ligand-Target Pair