BDBM50510723 CHEMBL4439125

SMILES: Clc1nc(N2CCC(CC2)N2CCOCC2)c2ccn(CCN3CCOCC3)c2n1

InChI Key: InChIKey=SORZVYPOZHBBAC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50510723 (CHEMBL4439125) Show SMILES Clc1nc(N2CCC(CC2)N2CCOCC2)c2ccn(CCN3CCOCC3)c2n1 Show InChI InChI=1S/C21H31ClN6O2/c22-21-23-19(27-4-1-17(2-5-27)26-11-15-30-16-12-26)18-3-6-28(20(18)24-21)8-7-25-9-13-29-14-10-25/h3,6,17H,1-2,4-5,7-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	317	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK-293 cells incubated for 90 mins by radioligand displace...				Bioorg Med Chem 27: 3194-3200 (2019) Article DOI: 10.1016/j.bmc.2019.05.042
					More data for this Ligand-Target Pair
Histamine receptor (H3 and H4) (Homo sapiens (Human))	BDBM50510723 (CHEMBL4439125) Show SMILES Clc1nc(N2CCC(CC2)N2CCOCC2)c2ccn(CCN3CCOCC3)c2n1 Show InChI InChI=1S/C21H31ClN6O2/c22-21-23-19(27-4-1-17(2-5-27)26-11-15-30-16-12-26)18-3-6-28(20(18)24-21)8-7-25-9-13-29-14-10-25/h3,6,17H,1-2,4-5,7-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cell membranes by radioligand displacement assay				Bioorg Med Chem 27: 3194-3200 (2019) Article DOI: 10.1016/j.bmc.2019.05.042
					More data for this Ligand-Target Pair