BDBM50510725 CHEMBL4560144

SMILES: Clc1cccc(Cl)c1Cn1ccc2c(ncnc12)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=GBQRNDSLOGBCSM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50510725 (CHEMBL4560144) Show SMILES Clc1cccc(Cl)c1Cn1ccc2c(ncnc12)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C23H27Cl2N5/c24-20-5-4-6-21(25)19(20)15-30-14-9-18-22(26-16-27-23(18)30)29-12-7-17(8-13-29)28-10-2-1-3-11-28/h4-6,9,14,16-17H,1-3,7-8,10-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK-293 cells incubated for 90 mins by radioligand displace...				Bioorg Med Chem 27: 3194-3200 (2019) Article DOI: 10.1016/j.bmc.2019.05.042
					More data for this Ligand-Target Pair
Histamine receptor (H3 and H4) (Homo sapiens (Human))	BDBM50510725 (CHEMBL4560144) Show SMILES Clc1cccc(Cl)c1Cn1ccc2c(ncnc12)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C23H27Cl2N5/c24-20-5-4-6-21(25)19(20)15-30-14-9-18-22(26-16-27-23(18)30)29-12-7-17(8-13-29)28-10-2-1-3-11-28/h4-6,9,14,16-17H,1-3,7-8,10-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cell membranes by radioligand displacement assay				Bioorg Med Chem 27: 3194-3200 (2019) Article DOI: 10.1016/j.bmc.2019.05.042
					More data for this Ligand-Target Pair