BDBM50511075 CHEMBL4447485
SMILES: CCOC(=O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1
InChI Key: InChIKey=GJZRNPKPWSCKLL-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens) | BDBM50511075 (CHEMBL4447485) | PDB KEGG GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 985 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungnam University Curated by ChEMBL | Assay Description Inhibition of recombinant human SHP2 expressed in Escherichia coli using 2P-IRS1 peptide as substrate after 1 hr by microplate reader analysis | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126756 | |||||||||||
More data for this Ligand-Target Pair |