BDBM50511194 CHEMBL4513352

SMILES: OC(=O)c1cc(NCc2ccc(OCc3ccc(F)cc3)cc2)ccc1F

InChI Key: InChIKey=KCVLTOIVFQOUNB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50511194 (CHEMBL4513352) Show SMILES OC(=O)c1cc(NCc2ccc(OCc3ccc(F)cc3)cc2)ccc1F Show InChI InChI=1S/C21H17F2NO3/c22-16-5-1-15(2-6-16)13-27-18-8-3-14(4-9-18)12-24-17-7-10-20(23)19(11-17)21(25)26/h1-11,24H,12-13H2,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a
University of Oklahoma Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in nonhuman mammalian cells assessed as increase in receptor transcriptional activity incubated for 22 ...				J Med Chem 63: 2854-2876 (2020) Article DOI: 10.1021/acs.jmedchem.9b01189
					More data for this Ligand-Target Pair