BDBM50511201 CHEMBL4458366

SMILES: OC(=O)c1cccc(NCc2ccc(OCc3cccc(F)c3)cc2)c1

InChI Key: InChIKey=AIKRYHTZFRGDNZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50511201 (CHEMBL4458366) Show SMILES OC(=O)c1cccc(NCc2ccc(OCc3cccc(F)c3)cc2)c1 Show InChI InChI=1S/C21H18FNO3/c22-18-5-1-3-16(11-18)14-26-20-9-7-15(8-10-20)13-23-19-6-2-4-17(12-19)21(24)25/h1-12,23H,13-14H2,(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a
University of Oklahoma Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in nonhuman mammalian cells assessed as increase in receptor transcriptional activity incubated for 22 ...				J Med Chem 63: 2854-2876 (2020) Article DOI: 10.1021/acs.jmedchem.9b01189
					More data for this Ligand-Target Pair