BDBM50511215 CHEMBL4540905

SMILES: Cc1cc(CNc2cccc(c2)C(O)=O)ccc1OCc1ccc(F)cc1F

InChI Key: InChIKey=IZPOHTQFQUPKDW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50511215 (CHEMBL4540905) Show SMILES Cc1cc(CNc2cccc(c2)C(O)=O)ccc1OCc1ccc(F)cc1F Show InChI InChI=1S/C22H19F2NO3/c1-14-9-15(12-25-19-4-2-3-16(10-19)22(26)27)5-8-21(14)28-13-17-6-7-18(23)11-20(17)24/h2-11,25H,12-13H2,1H3,(H,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a
University of Oklahoma Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in nonhuman mammalian cells assessed as increase in receptor transcriptional activity incubated for 22 ...				J Med Chem 63: 2854-2876 (2020) Article DOI: 10.1021/acs.jmedchem.9b01189
					More data for this Ligand-Target Pair