BDBM50511234 CHEMBL4551888

SMILES: CN1CCc2c(C1)sc1nc([nH]c(=O)c21)-c1cc(C)c(OCCCC(=O)NO)c(C)c1

InChI Key: InChIKey=KMUARRHNDZYKBX-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50511234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50511234 (CHEMBL4551888) Show SMILES CN1CCc2c(C1)sc1nc([nH]c(=O)c21)-c1cc(C)c(OCCCC(=O)NO)c(C)c1 Show InChI InChI=1S/C22H26N4O4S/c1-12-9-14(10-13(2)19(12)30-8-4-5-17(27)25-29)20-23-21(28)18-15-6-7-26(3)11-16(15)31-22(18)24-20/h9-10,29H,4-8,11H2,1-3H3,(H,25,27)(H,23,24,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University and Collaborative Innovation Center of Biotherapy Curated by ChEMBL					Assay Description Inhibition of GST-tagged BRD4 bromodomain (unknown origin) using biotinylated histone H4KAc peptide (1 to 21 residues) as substrate by HTRF assay				J Med Chem 63: 3678-3700 (2020) Article DOI: 10.1021/acs.jmedchem.9b02178
					More data for this Ligand-Target Pair
Histone deacetylase 7 (Homo sapiens (Human))	BDBM50511234 (CHEMBL4551888) Show SMILES CN1CCc2c(C1)sc1nc([nH]c(=O)c21)-c1cc(C)c(OCCCC(=O)NO)c(C)c1 Show InChI InChI=1S/C22H26N4O4S/c1-12-9-14(10-13(2)19(12)30-8-4-5-17(27)25-29)20-23-21(28)18-15-6-7-26(3)11-16(15)31-22(18)24-20/h9-10,29H,4-8,11H2,1-3H3,(H,25,27)(H,23,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University and Collaborative Innovation Center of Biotherapy Curated by ChEMBL					Assay Description Inhibition of HDAC7 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assay				J Med Chem 63: 3678-3700 (2020) Article DOI: 10.1021/acs.jmedchem.9b02178
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50511234 (CHEMBL4551888) Show SMILES CN1CCc2c(C1)sc1nc([nH]c(=O)c21)-c1cc(C)c(OCCCC(=O)NO)c(C)c1 Show InChI InChI=1S/C22H26N4O4S/c1-12-9-14(10-13(2)19(12)30-8-4-5-17(27)25-29)20-23-21(28)18-15-6-7-26(3)11-16(15)31-22(18)24-20/h9-10,29H,4-8,11H2,1-3H3,(H,25,27)(H,23,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University and Collaborative Innovation Center of Biotherapy Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assay				J Med Chem 63: 3678-3700 (2020) Article DOI: 10.1021/acs.jmedchem.9b02178
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 2 (Homo sapiens (Human))	BDBM50511234 (CHEMBL4551888) Show SMILES CN1CCc2c(C1)sc1nc([nH]c(=O)c21)-c1cc(C)c(OCCCC(=O)NO)c(C)c1 Show InChI InChI=1S/C22H26N4O4S/c1-12-9-14(10-13(2)19(12)30-8-4-5-17(27)25-29)20-23-21(28)18-15-6-7-26(3)11-16(15)31-22(18)24-20/h9-10,29H,4-8,11H2,1-3H3,(H,25,27)(H,23,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University and Collaborative Innovation Center of Biotherapy Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assay				J Med Chem 63: 3678-3700 (2020) Article DOI: 10.1021/acs.jmedchem.9b02178
					More data for this Ligand-Target Pair