BDBM50511324 CHEMBL4529780

SMILES: Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2F)cc1

InChI Key: InChIKey=PQOJWVHLJYMILK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50511324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A4 hydrolase (Homo sapiens (Human))	BDBM50511324 (CHEMBL4529780) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2F)cc1 Show InChI InChI=1S/C23H18F2N2O2S/c24-17-8-5-15(6-9-17)11-12-26-22(28)13-16-7-10-18(14-19(16)25)29-23-27-20-3-1-2-4-21(20)30-23/h1-10,14H,11-13H2,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511324 (CHEMBL4529780) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2F)cc1 Show InChI InChI=1S/C23H18F2N2O2S/c24-17-8-5-15(6-9-17)11-12-26-22(28)13-16-7-10-18(14-19(16)25)29-23-27-20-3-1-2-4-21(20)30-23/h1-10,14H,11-13H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330
					More data for this Ligand-Target Pair