BDBM50511629 CHEMBL4559074

SMILES: Cn1c2ccc(Nc3nc(ncc3Cl)N3CCC(F)(F)C(CO)C3)cc2n(CCC(C)(C)O)c1=O

InChI Key: InChIKey=AXXSGZFGJNDDCH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BCoR-BCL6 (Homo sapiens)	BDBM50511629 (CHEMBL4559074) Show SMILES Cn1c2ccc(Nc3nc(ncc3Cl)N3CCC(F)(F)C(CO)C3)cc2n(CCC(C)(C)O)c1=O Show InChI InChI=1S/C23H29ClF2N6O3/c1-22(2,35)6-9-32-18-10-15(4-5-17(18)30(3)21(32)34)28-19-16(24)11-27-20(29-19)31-8-7-23(25,26)14(12-31)13-33/h4-5,10-11,14,33,35H,6-9,12-13H2,1-3H3,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant His-tagged human BCL6 expressed in Escherichia coli BL21 AI cell incubated for 2 hrs by TR-FRET assay				J Med Chem 63: 4047-4068 (2020) Article DOI: 10.1021/acs.jmedchem.9b02076
					More data for this Ligand-Target Pair