BDBM50512057 CHEMBL4460424

SMILES: OC(=O)c1ccccc1NC(=O)C(=C\c1ccccc1)\c1ccccc1

InChI Key: InChIKey=NUTHTLQGGHXCLA-XDJHFCHBSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50512057 (CHEMBL4460424) Show SMILES OC(=O)c1ccccc1NC(=O)C(=C\c1ccccc1)\c1ccccc1 Show InChI InChI=1S/C22H17NO3/c24-21(23-20-14-8-7-13-18(20)22(25)26)19(17-11-5-2-6-12-17)15-16-9-3-1-4-10-16/h1-15H,(H,23,24)(H,25,26)/b19-15+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
University of Hull Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assay				Eur J Med Chem 170: 141-156 (2019) Article DOI: 10.1016/j.ejmech.2019.02.074
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50512057 (CHEMBL4460424) Show SMILES OC(=O)c1ccccc1NC(=O)C(=C\c1ccccc1)\c1ccccc1 Show InChI InChI=1S/C22H17NO3/c24-21(23-20-14-8-7-13-18(20)22(25)26)19(17-11-5-2-6-12-17)15-16-9-3-1-4-10-16/h1-15H,(H,23,24)(H,25,26)/b19-15+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a
University of Hull Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assay				Eur J Med Chem 170: 141-156 (2019) Article DOI: 10.1016/j.ejmech.2019.02.074
					More data for this Ligand-Target Pair