BindingDB logo
myBDB logout

BDBM50512247 CHEMBL4545692

SMILES: COC(=O)c1sc2nc3ccc(OC)cc3cc2c1N

InChI Key: InChIKey=XRJKHUHLPVGTCL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512247   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urea transporter B (UT-B)


(Rattus norvegicus (Rat))		BDBM50512247
PNG
(CHEMBL4545692)
Show SMILES COC(=O)c1sc2nc3ccc(OC)cc3cc2c1N
Show InChI InChI=1S/C14H12N2O3S/c1-18-8-3-4-10-7(5-8)6-9-11(15)12(14(17)19-2)20-13(9)16-10/h3-6H,15H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 220n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of urea transporter B in Sprague-Dawley rat erythrocytes incubated for 6 mins by spectrophotometric analysis based erythrocyte lysis assay

Eur J Med Chem 172: 131-142 (2019)


Article DOI: 10.1016/j.ejmech.2019.03.060
More data for this
Ligand-Target Pair