BDBM50512625 CHEMBL4474688

SMILES: COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1C#CCCN)N1CCCN(C)CC1

InChI Key: InChIKey=FNKMWVAWPMHKHA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512625   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EHMT1/EHMT2 (Homo sapiens (Human))	BDBM50512625 (CHEMBL4474688) Show SMILES COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1C#CCCN)N1CCCN(C)CC1 Show InChI InChI=1S/C25H37N7O/c1-30-11-6-12-32(16-15-30)25-28-22-17-19(7-4-5-10-26)23(33-3)18-21(22)24(29-25)27-20-8-13-31(2)14-9-20/h17-18,20H,5-6,8-16,26H2,1-3H3,(H,27,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Mercachem BV Curated by ChEMBL					Assay Description Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...				Bioorg Med Chem Lett 29: 2516-2524 (2019) Article DOI: 10.1016/j.bmcl.2019.06.012
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1/EHMT2 (Homo sapiens (Human))	BDBM50512625 (CHEMBL4474688) Show SMILES COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1C#CCCN)N1CCCN(C)CC1 Show InChI InChI=1S/C25H37N7O/c1-30-11-6-12-32(16-15-30)25-28-22-17-19(7-4-5-10-26)23(33-3)18-21(22)24(29-25)27-20-8-13-31(2)14-9-20/h17-18,20H,5-6,8-16,26H2,1-3H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Mercachem BV Curated by ChEMBL					Assay Description Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...				Bioorg Med Chem Lett 29: 2516-2524 (2019) Article DOI: 10.1016/j.bmcl.2019.06.012
					More data for this Ligand-Target Pair