BDBM50512786 CHEMBL4460889

SMILES: CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(N2CCO[C@@]3(CCCOC3)C2)c(F)c1

InChI Key: InChIKey=NRWYXTJNSKOQIE-JXFKEZNVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (Homo sapiens)	BDBM50512786 (CHEMBL4460889) Show SMILES CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(N2CCO[C@@]3(CCCOC3)C2)c(F)c1 |r| Show InChI InChI=1S/C20H26FN3O5/c1-14(25)22-10-16-11-24(19(26)29-16)15-3-4-18(17(21)9-15)23-6-8-28-20(12-23)5-2-7-27-13-20/h3-4,9,16H,2,5-8,10-13H2,1H3,(H,22,25)/t16-,20-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute of Technology Curated by ChEMBL					Assay Description Inhibition of SDH-A (unknown origin) by ELISA				Bioorg Med Chem Lett 29: 2686-2689 (2019) Article DOI: 10.1016/j.bmcl.2019.07.024
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM50512786 (CHEMBL4460889) Show SMILES CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(N2CCO[C@@]3(CCCOC3)C2)c(F)c1 |r| Show InChI InChI=1S/C20H26FN3O5/c1-14(25)22-10-16-11-24(19(26)29-16)15-3-4-18(17(21)9-15)23-6-8-28-20(12-23)5-2-7-27-13-20/h3-4,9,16H,2,5-8,10-13H2,1H3,(H,22,25)/t16-,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute of Technology Curated by ChEMBL					Assay Description Inhibition of COX1 (unknown origin) by ELISA				Bioorg Med Chem Lett 29: 2686-2689 (2019) Article DOI: 10.1016/j.bmcl.2019.07.024
					More data for this Ligand-Target Pair