null

SMILES: COc1cccc(Cc2cc(C)nn(C(C)C(=O)Nc3ccccc3Cl)c2=O)c1

InChI Key: InChIKey=JIVRGQWBJMJMTP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513103 (CHEMBL4447184) Show SMILES COc1cccc(Cc2cc(C)nn(C(C)C(=O)Nc3ccccc3Cl)c2=O)c1 Show InChI InChI=1S/C22H22ClN3O3/c1-14-11-17(12-16-7-6-8-18(13-16)29-3)22(28)26(25-14)15(2)21(27)24-20-10-5-4-9-19(20)23/h4-11,13,15H,12H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513103 (CHEMBL4447184) Show SMILES COc1cccc(Cc2cc(C)nn(C(C)C(=O)Nc3ccccc3Cl)c2=O)c1 Show InChI InChI=1S/C22H22ClN3O3/c1-14-11-17(12-16-7-6-8-18(13-16)29-3)22(28)26(25-14)15(2)21(27)24-20-10-5-4-9-19(20)23/h4-11,13,15H,12H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912
					More data for this Ligand-Target Pair