BDBM50513109 CHEMBL4536334

SMILES: CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2cccc(OC)c2OC)c1=O

InChI Key: InChIKey=BZVPHRYZBNRAIA-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50513109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50513109 (CHEMBL4536334) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2cccc(OC)c2OC)c1=O Show InChI InChI=1S/C26H30ClN3O4/c1-5-6-9-22(25(31)28-21-13-11-20(27)12-14-21)30-26(32)19(15-17(2)29-30)16-18-8-7-10-23(33-3)24(18)34-4/h7-8,10-15,22H,5-6,9,16H2,1-4H3,(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513109 (CHEMBL4536334) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2cccc(OC)c2OC)c1=O Show InChI InChI=1S/C26H30ClN3O4/c1-5-6-9-22(25(31)28-21-13-11-20(27)12-14-21)30-26(32)19(15-17(2)29-30)16-18-8-7-10-23(33-3)24(18)34-4/h7-8,10-15,22H,5-6,9,16H2,1-4H3,(H,28,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513109 (CHEMBL4536334) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2cccc(OC)c2OC)c1=O Show InChI InChI=1S/C26H30ClN3O4/c1-5-6-9-22(25(31)28-21-13-11-20(27)12-14-21)30-26(32)19(15-17(2)29-30)16-18-8-7-10-23(33-3)24(18)34-4/h7-8,10-15,22H,5-6,9,16H2,1-4H3,(H,28,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50513109 (CHEMBL4536334) Show SMILES CCCCC(C(=O)Nc1ccc(Cl)cc1)n1nc(C)cc(Cc2cccc(OC)c2OC)c1=O Show InChI InChI=1S/C26H30ClN3O4/c1-5-6-9-22(25(31)28-21-13-11-20(27)12-14-21)30-26(32)19(15-17(2)29-30)16-18-8-7-10-23(33-3)24(18)34-4/h7-8,10-15,22H,5-6,9,16H2,1-4H3,(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912
					More data for this Ligand-Target Pair