null

SMILES: COc1cccc(OC)c1Cc1cc(C)nn(CC(=O)Nc2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=QZXNEBXLWBNQTM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513114 (CHEMBL4476616) Show SMILES COc1cccc(OC)c1Cc1cc(C)nn(CC(=O)Nc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C22H22ClN3O4/c1-14-11-15(12-18-19(29-2)5-4-6-20(18)30-3)22(28)26(25-14)13-21(27)24-17-9-7-16(23)8-10-17/h4-11H,12-13H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513114 (CHEMBL4476616) Show SMILES COc1cccc(OC)c1Cc1cc(C)nn(CC(=O)Nc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C22H22ClN3O4/c1-14-11-15(12-18-19(29-2)5-4-6-20(18)30-3)22(28)26(25-14)13-21(27)24-17-9-7-16(23)8-10-17/h4-11H,12-13H2,1-3H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912
					More data for this Ligand-Target Pair