BDBM50513118 CHEMBL4539397

SMILES: CCc1ccc(NC(=O)Cn2nc(C)cc(Cc3ccccc3OC)c2=O)cc1

InChI Key: InChIKey=SAHXQKHCYJMGLY-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513118 (CHEMBL4539397) Show SMILES CCc1ccc(NC(=O)Cn2nc(C)cc(Cc3ccccc3OC)c2=O)cc1 Show InChI InChI=1S/C23H25N3O3/c1-4-17-9-11-20(12-10-17)24-22(27)15-26-23(28)19(13-16(2)25-26)14-18-7-5-6-8-21(18)29-3/h5-13H,4,14-15H2,1-3H3,(H,24,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50513118 (CHEMBL4539397) Show SMILES CCc1ccc(NC(=O)Cn2nc(C)cc(Cc3ccccc3OC)c2=O)cc1 Show InChI InChI=1S/C23H25N3O3/c1-4-17-9-11-20(12-10-17)24-22(27)15-26-23(28)19(13-16(2)25-26)14-18-7-5-6-8-21(18)29-3/h5-13H,4,14-15H2,1-3H3,(H,24,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912
					More data for this Ligand-Target Pair