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SMILES: [H][C@]12CC[C@]([H])(C\C(C1)=N/Nc1nc(cs1)-c1ccc(C)cc1)N2C

InChI Key: InChIKey=ZIWLYFLDCSFCMM-GTGLYJSASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50513190   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50513190
PNG
(CHEMBL4438867)
Show SMILES [H][C@]12CC[C@]([H])(C\C(C1)=N/Nc1nc(cs1)-c1ccc(C)cc1)N2C |r,TLB:9:7:23:2.3|
Show InChI InChI=1S/C18H22N4S/c1-12-3-5-13(6-4-12)17-11-23-18(19-17)21-20-14-9-15-7-8-16(10-14)22(15)2/h3-6,11,15-16H,7-10H2,1-2H3,(H,19,21)/b20-14-/t15-,16+/m0/s1
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.01E+5n/an/an/an/an/an/a



Nicolaus Copernicus University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-dopa as substrate incubated for 30 mins by spectrophotometric method

Eur J Med Chem 175: 162-171 (2019)


Article DOI: 10.1016/j.ejmech.2019.05.006
BindingDB Entry DOI: 10.7270/Q2794815
More data for this
Ligand-Target Pair