BDBM50513205 CHEMBL4437666

SMILES: Fc1cccc(F)c1N[C@@]1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc12

InChI Key: InChIKey=FUFYOQRYQLCEGB-OAQYLSRUSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM50513205 (CHEMBL4437666) Show SMILES Fc1cccc(F)c1N[C@@]1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc12 |r| Show InChI InChI=1S/C21H14Cl2F2N2O/c22-13-4-1-3-12(9-13)11-21(27-19-16(24)5-2-6-17(19)25)15-8-7-14(23)10-18(15)26-20(21)28/h1-10,27H,11H2,(H,26,28)/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysis				Eur J Med Chem 176: 92-104 (2019) Article DOI: 10.1016/j.ejmech.2019.05.018
					More data for this Ligand-Target Pair
MDM2-MDMX (Homo sapiens (Human))	BDBM50513205 (CHEMBL4437666) Show SMILES Fc1cccc(F)c1N[C@@]1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc12 |r| Show InChI InChI=1S/C21H14Cl2F2N2O/c22-13-4-1-3-12(9-13)11-21(27-19-16(24)5-2-6-17(19)25)15-8-7-14(23)10-18(15)26-20(21)28/h1-10,27H,11H2,(H,26,28)/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of MDM2 (unknown origin)				Eur J Med Chem 176: 92-104 (2019) Article DOI: 10.1016/j.ejmech.2019.05.018
					More data for this Ligand-Target Pair