null
SMILES: FC(F)(F)c1ccc(cc1)S(=O)(=O)Nc1ccc2nc3-c4[nH]c5ccccc5c4CCn3c(=O)c2c1
InChI Key: InChIKey=GSJKDHDEEMJQDD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholinesterase (Equus caballus (Horse)) | BDBM50513306![]() (CHEMBL4548040) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University Curated by ChEMBL | Assay Description Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition a... | Eur J Med Chem 177: 198-211 (2019) Article DOI: 10.1016/j.ejmech.2019.05.055 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM50513306![]() (CHEMBL4548040) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui Medical University Curated by ChEMBL | Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured afte... | Eur J Med Chem 177: 198-211 (2019) Article DOI: 10.1016/j.ejmech.2019.05.055 | |||||||||||
More data for this Ligand-Target Pair |