null

SMILES: COc1ccc2n(cc(-c3cnc(NC(C)=O)[nH]3)c2c1)S(=O)(=O)c1cccc(F)c1

InChI Key: InChIKey=YDQVLCUOXBQXGJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50513404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513404 (CHEMBL4451666) Show SMILES COc1ccc2n(cc(-c3cnc(NC(C)=O)[nH]3)c2c1)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C20H17FN4O4S/c1-12(26)23-20-22-10-18(24-20)17-11-25(19-7-6-14(29-2)9-16(17)19)30(27,28)15-5-3-4-13(21)8-15/h3-11H,1-2H3,(H2,22,23,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50513404 (CHEMBL4451666) Show SMILES COc1ccc2n(cc(-c3cnc(NC(C)=O)[nH]3)c2c1)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C20H17FN4O4S/c1-12(26)23-20-22-10-18(24-20)17-11-25(19-7-6-14(29-2)9-16(17)19)30(27,28)15-5-3-4-13(21)8-15/h3-11H,1-2H3,(H2,22,23,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHOK1 cells incubated for 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50513404 (CHEMBL4451666) Show SMILES COc1ccc2n(cc(-c3cnc(NC(C)=O)[nH]3)c2c1)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C20H17FN4O4S/c1-12(26)23-20-22-10-18(24-20)17-11-25(19-7-6-14(29-2)9-16(17)19)30(27,28)15-5-3-4-13(21)8-15/h3-11H,1-2H3,(H2,22,23,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50513404 (CHEMBL4451666) Show SMILES COc1ccc2n(cc(-c3cnc(NC(C)=O)[nH]3)c2c1)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C20H17FN4O4S/c1-12(26)23-20-22-10-18(24-20)17-11-25(19-7-6-14(29-2)9-16(17)19)30(27,28)15-5-3-4-13(21)8-15/h3-11H,1-2H3,(H2,22,23,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-methylspiperone from human D2 long receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001
					More data for this Ligand-Target Pair