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SMILES: Cl.Cc1nc(N)[nH]c1-c1cn(c2ccccc12)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=ZWXVFHQSORXZDQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50513414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50513414 (CHEMBL4586353) Show SMILES Cl.Cc1nc(N)[nH]c1-c1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H16N4O2S/c1-12-17(21-18(19)20-12)15-11-22(16-10-6-5-9-14(15)16)25(23,24)13-7-3-2-4-8-13/h2-11H,1H3,(H3,19,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50513414 (CHEMBL4586353) Show SMILES Cl.Cc1nc(N)[nH]c1-c1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H16N4O2S/c1-12-17(21-18(19)20-12)15-11-22(16-10-6-5-9-14(15)16)25(23,24)13-7-3-2-4-8-13/h2-11H,1H3,(H3,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHOK1 cells incubated for 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50513414 (CHEMBL4586353) Show SMILES Cl.Cc1nc(N)[nH]c1-c1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H16N4O2S/c1-12-17(21-18(19)20-12)15-11-22(16-10-6-5-9-14(15)16)25(23,24)13-7-3-2-4-8-13/h2-11H,1H3,(H3,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-methylspiperone from human D2 long receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50513414 (CHEMBL4586353) Show SMILES Cl.Cc1nc(N)[nH]c1-c1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H16N4O2S/c1-12-17(21-18(19)20-12)15-11-22(16-10-6-5-9-14(15)16)25(23,24)13-7-3-2-4-8-13/h2-11H,1H3,(H3,19,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513414 (CHEMBL4586353) Show SMILES Cl.Cc1nc(N)[nH]c1-c1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H16N4O2S/c1-12-17(21-18(19)20-12)15-11-22(16-10-6-5-9-14(15)16)25(23,24)13-7-3-2-4-8-13/h2-11H,1H3,(H3,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counter method				Eur J Med Chem 179: 1-15 (2019) Article DOI: 10.1016/j.ejmech.2019.06.001
					More data for this Ligand-Target Pair