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SMILES: Fc1ccc(cc1)-c1c(NC(=O)CC2CCCC2)nn2cccnc12

InChI Key: InChIKey=UJMVKDZGOKTDOJ-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50513736   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily KQT member 2/3


(Homo sapiens (Human))		BDBM50513736
PNG
(CHEMBL4592138)
Show SMILES Fc1ccc(cc1)-c1c(NC(=O)CC2CCCC2)nn2cccnc12
Show InChI InChI=1S/C19H19FN4O/c20-15-8-6-14(7-9-15)17-18(23-24-11-3-10-21-19(17)24)22-16(25)12-13-4-1-2-5-13/h3,6-11,13H,1-2,4-5,12H2,(H,22,23,25)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.00E+3n/an/an/an/a



AbbVie Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human KCNQ2/3 expressed in HEK293 cells by FLIPR based thallium influx assay

Bioorg Med Chem Lett 29: (2019)


Article DOI: 10.1016/j.bmcl.2019.08.007
BindingDB Entry DOI: 10.7270/Q2Q52SZP
More data for this
Ligand-Target Pair