BDBM50514119 CHEMBL4515625

SMILES: Cc1ccn(n1)[C@@H](CC(=O)N1CCC(O)(Cn2cnc3n(Cc4ccc(F)cc4)ncc3c2=O)CC1)C(F)F

InChI Key: InChIKey=PTSKLBFLMNNWHX-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50514119 (CHEMBL4515625) Show SMILES Cc1ccn(n1)[C@@H](CC(=O)N1CCC(O)(Cn2cnc3n(Cc4ccc(F)cc4)ncc3c2=O)CC1)C(F)F |r| Show InChI InChI=1S/C26H28F3N7O3/c1-17-6-9-35(32-17)21(23(28)29)12-22(37)33-10-7-26(39,8-11-33)15-34-16-30-24-20(25(34)38)13-31-36(24)14-18-2-4-19(27)5-3-18/h2-6,9,13,16,21,23,39H,7-8,10-12,14-15H2,1H3/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute Curated by ChEMBL					Assay Description Inhibition of USP7 C-terminal domain (unknown origin) (208 to 1102 residues) expressed in Sf9 cells using monoubiquitinated ubiquitin-rhodamine subst...				J Med Chem 63: 2731-2750 (2020) Article DOI: 10.1021/acs.jmedchem.9b01138
					More data for this Ligand-Target Pair