BDBM50514577 CHEMBL3581591
SMILES: [H][C@@]1([#6]-[#6@H](-[#6]-[#6][C@@]1([#6])[#8])-[#6](-[#6])=[#6])[#6]-1=[#6](-[#8])C([#6]\[#6]=[#6](\[#6])-[#6])([#6]\[#6]=[#6](/[#6])-[#6])[#6](=O)-[#6](-[#6](=O)-[#6](-[#6])-[#6]-[#6])=[#6]-1-[#8]
InChI Key: InChIKey=LVXMXPFAKOESBU-HBGBDTIESA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
T-type calcium channel alpha 1G subunit (Mus musculus) | BDBM50514577![]() (CHEMBL3581591) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Antagonist activity at mouse Cav3.1 expressed in HEK293T cells assessed as inhibition of current amplitude at holding potential of -100 mV by whole c... | J Med Chem 63: 1709-1716 (2020) Article DOI: 10.1021/acs.jmedchem.9b02056 | |||||||||||
More data for this Ligand-Target Pair |