BDBM50514826 CHEMBL4586557

SMILES: CCCCCCC(Sc1nc2ccc(NCc3ccccc3)cc2s1)C(O)=O

InChI Key: InChIKey=IQXYNQBOHVNJHU-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514826   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50514826 (CHEMBL4586557) Show SMILES CCCCCCC(Sc1nc2ccc(NCc3ccccc3)cc2s1)C(O)=O Show InChI InChI=1S/C22H26N2O2S2/c1-2-3-4-8-11-19(21(25)26)27-22-24-18-13-12-17(14-20(18)28-22)23-15-16-9-6-5-7-10-16/h5-7,9-10,12-14,19,23H,2-4,8,11,15H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Partial agonist activity at Gal4-fused PPARgamma LBD (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assay				J Med Chem 63: 4555-4561 (2020) Article DOI: 10.1021/acs.jmedchem.9b01786
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50514826 (CHEMBL4586557) Show SMILES CCCCCCC(Sc1nc2ccc(NCc3ccccc3)cc2s1)C(O)=O Show InChI InChI=1S/C22H26N2O2S2/c1-2-3-4-8-11-19(21(25)26)27-22-24-18-13-12-17(14-20(18)28-22)23-15-16-9-6-5-7-10-16/h5-7,9-10,12-14,19,23H,2-4,8,11,15H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Partial agonist activity at Gal4-fused PPARalpha LBD (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assay				J Med Chem 63: 4555-4561 (2020) Article DOI: 10.1021/acs.jmedchem.9b01786
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50514826 (CHEMBL4586557) Show SMILES CCCCCCC(Sc1nc2ccc(NCc3ccccc3)cc2s1)C(O)=O Show InChI InChI=1S/C22H26N2O2S2/c1-2-3-4-8-11-19(21(25)26)27-22-24-18-13-12-17(14-20(18)28-22)23-15-16-9-6-5-7-10-16/h5-7,9-10,12-14,19,23H,2-4,8,11,15H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Partial agonist activity at Gal4-fused PPARdelta LBD (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assay				J Med Chem 63: 4555-4561 (2020) Article DOI: 10.1021/acs.jmedchem.9b01786
					More data for this Ligand-Target Pair