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SMILES: [O-][N+](=O)c1ccc(cc1)C(=O)N1CCN(Cc2ccc(F)cc2)CC1

InChI Key: InChIKey=MXARPWQKOZXTFJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50515005   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50515005
PNG
(CHEMBL4516730)
Show SMILES [O-][N+](=O)c1ccc(cc1)C(=O)N1CCN(Cc2ccc(F)cc2)CC1
Show InChI InChI=1S/C18H18FN3O3/c19-16-5-1-14(2-6-16)13-20-9-11-21(12-10-20)18(23)15-3-7-17(8-4-15)22(24)25/h1-8H,9-13H2
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.05E+3n/an/an/an/an/an/a



Polo Universitario SS. Annunziata

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase assessed as reduction in dopachrome production using L-DOPA as substrate after 5 mins by spectrophotometric analysi...

Eur J Med Chem 178: 380-389 (2019)


Article DOI: 10.1016/j.ejmech.2019.06.019
More data for this
Ligand-Target Pair