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SMILES: Fc1ccc(CN2CCN(CC2)C(=O)c2cccc(c2)C(F)(F)F)cc1

InChI Key: InChIKey=NNOXHZBUFTVGNP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50515019   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50515019
PNG
(CHEMBL4561704)
Show SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2cccc(c2)C(F)(F)F)cc1
Show InChI InChI=1S/C19H18F4N2O/c20-17-6-4-14(5-7-17)13-24-8-10-25(11-9-24)18(26)15-2-1-3-16(12-15)19(21,22)23/h1-7,12H,8-11,13H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.43E+3n/an/an/an/an/an/a



Polo Universitario SS. Annunziata

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase assessed as reduction in dopachrome production using L-DOPA as substrate after 5 mins by spectrophotometric analysi...

Eur J Med Chem 178: 380-389 (2019)


Article DOI: 10.1016/j.ejmech.2019.06.019
BindingDB Entry DOI: 10.7270/Q2G44TMV
More data for this
Ligand-Target Pair