null

SMILES: CC(=O)N1N=C(CC1c1ccc(OS(N)(=O)=O)cc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=NAYVNMKIDMRCMQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50515824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50515824 (CHEMBL4519062) Show SMILES CC(=O)N1N=C(CC1c1ccc(OS(N)(=O)=O)cc1)c1ccc(Cl)c(Cl)c1 |c:4| Show InChI InChI=1S/C17H15Cl2N3O4S/c1-10(23)22-17(11-2-5-13(6-3-11)26-27(20,24)25)9-16(21-22)12-4-7-14(18)15(19)8-12/h2-8,17H,9H2,1H3,(H2,20,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 assessed as inhibitory constant incubated for 15 mins by phenol red dye based stopped flow assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111638
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50515824 (CHEMBL4519062) Show SMILES CC(=O)N1N=C(CC1c1ccc(OS(N)(=O)=O)cc1)c1ccc(Cl)c(Cl)c1 |c:4| Show InChI InChI=1S/C17H15Cl2N3O4S/c1-10(23)22-17(11-2-5-13(6-3-11)26-27(20,24)25)9-16(21-22)12-4-7-14(18)15(19)8-12/h2-8,17H,9H2,1H3,(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 assessed as inhibitory constant incubated for 15 mins by phenol red dye based stopped flow assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111638
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50515824 (CHEMBL4519062) Show SMILES CC(=O)N1N=C(CC1c1ccc(OS(N)(=O)=O)cc1)c1ccc(Cl)c(Cl)c1 |c:4| Show InChI InChI=1S/C17H15Cl2N3O4S/c1-10(23)22-17(11-2-5-13(6-3-11)26-27(20,24)25)9-16(21-22)12-4-7-14(18)15(19)8-12/h2-8,17H,9H2,1H3,(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 assessed as inhibitory constant incubated for 15 mins by phenol red dye based stopped flow assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111638
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50515824 (CHEMBL4519062) Show SMILES CC(=O)N1N=C(CC1c1ccc(OS(N)(=O)=O)cc1)c1ccc(Cl)c(Cl)c1 |c:4| Show InChI InChI=1S/C17H15Cl2N3O4S/c1-10(23)22-17(11-2-5-13(6-3-11)26-27(20,24)25)9-16(21-22)12-4-7-14(18)15(19)8-12/h2-8,17H,9H2,1H3,(H2,20,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 assessed as inhibitory constant incubated for 15 mins by phenol red dye based stopped flow assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111638
					More data for this Ligand-Target Pair