null

SMILES: COc1ccc(cc1)-c1oc2ccccc2c1C(=O)c1ccc(cc1)N(Cc1cc(F)cc(F)c1)Cc1cc(F)cc(F)c1

InChI Key: InChIKey=WCGAXZMSFZPYAZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50516296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50516296 (CHEMBL4442586) Show SMILES COc1ccc(cc1)-c1oc2ccccc2c1C(=O)c1ccc(cc1)N(Cc1cc(F)cc(F)c1)Cc1cc(F)cc(F)c1 Show InChI InChI=1S/C36H25F4NO3/c1-43-31-12-8-25(9-13-31)36-34(32-4-2-3-5-33(32)44-36)35(42)24-6-10-30(11-7-24)41(20-22-14-26(37)18-27(38)15-22)21-23-16-28(39)19-29(40)17-23/h2-19H,20-21H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Displacement of 3[H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cell membranes measured after 90 mins by Cheng-Prusoff equation ...				Eur J Med Chem 178: 243-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.080
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50516296 (CHEMBL4442586) Show SMILES COc1ccc(cc1)-c1oc2ccccc2c1C(=O)c1ccc(cc1)N(Cc1cc(F)cc(F)c1)Cc1cc(F)cc(F)c1 Show InChI InChI=1S/C36H25F4NO3/c1-43-31-12-8-25(9-13-31)36-34(32-4-2-3-5-33(32)44-36)35(42)24-6-10-30(11-7-24)41(20-22-14-26(37)18-27(38)15-22)21-23-16-28(39)19-29(40)17-23/h2-19H,20-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Displacement of 3[H]-CP55940 from human recombinant CB2 receptor expressed in HEK293 cell membranes measured after 90 mins by Cheng-Prusoff equation ...				Eur J Med Chem 178: 243-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.080
					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50516296 (CHEMBL4442586) Show SMILES COc1ccc(cc1)-c1oc2ccccc2c1C(=O)c1ccc(cc1)N(Cc1cc(F)cc(F)c1)Cc1cc(F)cc(F)c1 Show InChI InChI=1S/C36H25F4NO3/c1-43-31-12-8-25(9-13-31)36-34(32-4-2-3-5-33(32)44-36)35(42)24-6-10-30(11-7-24)41(20-22-14-26(37)18-27(38)15-22)21-23-16-28(39)19-29(40)17-23/h2-19H,20-21H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Inhibition of human recombinant BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman'...				Eur J Med Chem 178: 243-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.080
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50516296 (CHEMBL4442586) Show SMILES COc1ccc(cc1)-c1oc2ccccc2c1C(=O)c1ccc(cc1)N(Cc1cc(F)cc(F)c1)Cc1cc(F)cc(F)c1 Show InChI InChI=1S/C36H25F4NO3/c1-43-31-12-8-25(9-13-31)36-34(32-4-2-3-5-33(32)44-36)35(42)24-6-10-30(11-7-24)41(20-22-14-26(37)18-27(38)15-22)21-23-16-28(39)19-29(40)17-23/h2-19H,20-21H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Displacement of 3[H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cell membranes measured after 90 mins				Eur J Med Chem 178: 243-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.080
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50516296 (CHEMBL4442586) Show SMILES COc1ccc(cc1)-c1oc2ccccc2c1C(=O)c1ccc(cc1)N(Cc1cc(F)cc(F)c1)Cc1cc(F)cc(F)c1 Show InChI InChI=1S/C36H25F4NO3/c1-43-31-12-8-25(9-13-31)36-34(32-4-2-3-5-33(32)44-36)35(42)24-6-10-30(11-7-24)41(20-22-14-26(37)18-27(38)15-22)21-23-16-28(39)19-29(40)17-23/h2-19H,20-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Displacement of 3[H]-CP55940 from human recombinant CB2 receptor expressed in HEK293 cell membranes measured after 90 mins				Eur J Med Chem 178: 243-258 (2019) Article DOI: 10.1016/j.ejmech.2019.05.080
					More data for this Ligand-Target Pair