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SMILES: CC(C)Oc1nc(Nc2ccc(cc2)-c2nnn[nH]2)ncc1C

InChI Key: InChIKey=IMTMUIGEYABQPF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50516345   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50516345
PNG
(CHEMBL4516559)
Show SMILES CC(C)Oc1nc(Nc2ccc(cc2)-c2nnn[nH]2)ncc1C
Show InChI InChI=1S/C15H17N7O/c1-9(2)23-14-10(3)8-16-15(18-14)17-12-6-4-11(5-7-12)13-19-21-22-20-13/h4-9H,1-3H3,(H,16,17,18)(H,19,20,21,22)
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Article
PubMed
n/an/a 0.438n/an/an/an/an/an/a



Henan University of Chinese Medicine

Curated by ChEMBL


Assay Description
Inhibition of Aurora A (unknown origin)

Eur J Med Chem 178: 341-351 (2019)


Article DOI: 10.1016/j.ejmech.2019.05.071
More data for this
Ligand-Target Pair