BDBM50516765 CHEMBL4581912

SMILES: CC(O)(COc1ccccc1C(F)(F)F)C(=O)Nc1ccc(cc1)S(F)(F)(F)(F)F

InChI Key: InChIKey=BPQMRZSSLFEMFE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Rattus norvegicus (Rat))	BDBM50516765 (CHEMBL4581912) Show SMILES CC(O)(COc1ccccc1C(F)(F)F)C(=O)Nc1ccc(cc1)S(F)(F)(F)(F)F Show InChI InChI=1S/C17H15F8NO3S/c1-16(28,10-29-14-5-3-2-4-13(14)17(18,19)20)15(27)26-11-6-8-12(9-7-11)30(21,22,23,24)25/h2-9,28H,10H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Antagonist activity at GAL4-DBD fused rat androgen receptor expressed in UAS-bla 293 cells assessed as reduction in R1881-induced activation incubate...				Eur J Med Chem 180: 1-14 (2019) Article DOI: 10.1016/j.ejmech.2019.07.001
					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50516765 (CHEMBL4581912) Show SMILES CC(O)(COc1ccccc1C(F)(F)F)C(=O)Nc1ccc(cc1)S(F)(F)(F)(F)F Show InChI InChI=1S/C17H15F8NO3S/c1-16(28,10-29-14-5-3-2-4-13(14)17(18,19)20)15(27)26-11-6-8-12(9-7-11)30(21,22,23,24)25/h2-9,28H,10H2,1H3,(H,26,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by whole-cell voltage-clamp analysis				Eur J Med Chem 180: 1-14 (2019) Article DOI: 10.1016/j.ejmech.2019.07.001
					More data for this Ligand-Target Pair