Found 2 hits for monomerid = 50516847 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50516847
(CHEMBL4458712)Show SMILES COc1ccc2[nH]cc(C3CCCN(CCCCn4c(=O)c(c5CCCCn5c4=O)-c4ccccc4C)C3)c2c1 |(45.69,-56.48,;44.67,-55.33,;43.16,-55.64,;42.68,-57.1,;41.17,-57.41,;40.15,-56.25,;38.62,-56.24,;38.16,-54.77,;39.41,-53.88,;39.42,-52.34,;40.76,-51.58,;40.78,-50.04,;39.45,-49.26,;38.12,-50.01,;36.79,-49.24,;35.45,-50,;34.12,-49.22,;32.78,-49.98,;31.45,-49.21,;31.46,-47.67,;32.8,-46.9,;30.13,-46.89,;28.8,-47.66,;27.47,-46.88,;26.14,-47.66,;26.14,-49.2,;27.47,-49.96,;28.79,-49.2,;30.12,-49.97,;30.11,-51.51,;30.14,-45.35,;28.81,-44.58,;28.81,-43.05,;30.15,-42.27,;31.48,-43.05,;31.47,-44.59,;32.8,-45.36,;38.1,-51.56,;40.65,-54.8,;42.15,-54.49,)| Show InChI InChI=1S/C33H40N4O3/c1-23-10-3-4-12-26(23)31-30-13-5-6-18-36(30)33(39)37(32(31)38)19-8-7-16-35-17-9-11-24(22-35)28-21-34-29-15-14-25(40-2)20-27(28)29/h3-4,10,12,14-15,20-21,24,34H,5-9,11,13,16-19,22H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 66 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Warsaw
Curated by ChEMBL
| Assay Description
Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta scintillation counting... |
Eur J Med Chem 180: 383-397 (2019)
Article DOI: 10.1016/j.ejmech.2019.07.027 |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50516847
(CHEMBL4458712)Show SMILES COc1ccc2[nH]cc(C3CCCN(CCCCn4c(=O)c(c5CCCCn5c4=O)-c4ccccc4C)C3)c2c1 |(45.69,-56.48,;44.67,-55.33,;43.16,-55.64,;42.68,-57.1,;41.17,-57.41,;40.15,-56.25,;38.62,-56.24,;38.16,-54.77,;39.41,-53.88,;39.42,-52.34,;40.76,-51.58,;40.78,-50.04,;39.45,-49.26,;38.12,-50.01,;36.79,-49.24,;35.45,-50,;34.12,-49.22,;32.78,-49.98,;31.45,-49.21,;31.46,-47.67,;32.8,-46.9,;30.13,-46.89,;28.8,-47.66,;27.47,-46.88,;26.14,-47.66,;26.14,-49.2,;27.47,-49.96,;28.79,-49.2,;30.12,-49.97,;30.11,-51.51,;30.14,-45.35,;28.81,-44.58,;28.81,-43.05,;30.15,-42.27,;31.48,-43.05,;31.47,-44.59,;32.8,-45.36,;38.1,-51.56,;40.65,-54.8,;42.15,-54.49,)| Show InChI InChI=1S/C33H40N4O3/c1-23-10-3-4-12-26(23)31-30-13-5-6-18-36(30)33(39)37(32(31)38)19-8-7-16-35-17-9-11-24(22-35)28-21-34-29-15-14-25(40-2)20-27(28)29/h3-4,10,12,14-15,20-21,24,34H,5-9,11,13,16-19,22H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Warsaw
Curated by ChEMBL
| Assay Description
Displacement of [3H]-citalopram from SERT in rat cortex tissue incubated for 60 mins by microbeta scintillation counting method |
Eur J Med Chem 180: 383-397 (2019)
Article DOI: 10.1016/j.ejmech.2019.07.027 |
More data for this
Ligand-Target Pair | |
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