BDBM50517194 CHEMBL4460559

SMILES: CCCC\C(=C/c1cc(OCc2ccc3nc(cc(OC)c3c2)C(F)(F)F)ccc1OCc1ccc(OC(F)F)cc1)C(O)=O

InChI Key: InChIKey=LQBVDJHPCQYCQH-PXLXIMEGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50517194 (CHEMBL4460559) Show SMILES CCCC\C(=C/c1cc(OCc2ccc3nc(cc(OC)c3c2)C(F)(F)F)ccc1OCc1ccc(OC(F)F)cc1)C(O)=O Show InChI InChI=1S/C33H30F5NO6/c1-3-4-5-22(31(40)41)15-23-16-25(11-13-28(23)44-18-20-6-9-24(10-7-20)45-32(34)35)43-19-21-8-12-27-26(14-21)29(42-2)17-30(39-27)33(36,37)38/h6-17,32H,3-5,18-19H2,1-2H3,(H,40,41)/b22-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Molecular Biology and Applied Ecology IME Curated by ChEMBL					Assay Description Antagonist actvity in pFA-GAL4-DBD fused PPARgamma LBD (unknown origin) transfected in HEK293T cells assessed as inhibition of rosiglitazone-induced ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115082
					More data for this Ligand-Target Pair