BDBM50517414 CHEMBL4563904

SMILES: C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(Cc1cn(C)cn1)c2=O

InChI Key: InChIKey=NMBLJOILHIVHIT-CYBMUJFWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50517414 (CHEMBL4563904) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(Cc1cn(C)cn1)c2=O |r| Show InChI InChI=1S/C24H27N7O2/c1-13-19-17(21(32)26-13)9-18(27-19)15-7-6-8-16-20(15)28-23(29-24(2,3)4)31(22(16)33)11-14-10-30(5)12-25-14/h6-10,12-13,27H,11H2,1-5H3,(H,26,32)(H,28,29)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50517414 (CHEMBL4563904) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1cccc2c1nc(NC(C)(C)C)n(Cc1cn(C)cn1)c2=O |r| Show InChI InChI=1S/C24H27N7O2/c1-13-19-17(21(32)26-13)9-18(27-19)15-7-6-8-16-20(15)28-23(29-24(2,3)4)31(22(16)33)11-14-10-30(5)12-25-14/h6-10,12-13,27H,11H2,1-5H3,(H,26,32)(H,28,29)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...				J Med Chem 62: 1523-1540 (2019) Article DOI: 10.1021/acs.jmedchem.8b01733
					More data for this Ligand-Target Pair