BDBM50517441 CHEMBL4551803

SMILES: CS(=O)(=O)Nc1ccc(-c2ccc(F)c(F)c2)c2cccnc12

InChI Key: InChIKey=UUWUGQGVKVIRST-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glyoxalase I (Homo sapiens (Human))	BDBM50517441 (CHEMBL4551803) Show SMILES CS(=O)(=O)Nc1ccc(-c2ccc(F)c(F)c2)c2cccnc12 Show InChI InChI=1S/C16H12F2N2O2S/c1-23(21,22)20-15-7-5-11(12-3-2-8-19-16(12)15)10-4-6-13(17)14(18)9-10/h2-9,20H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...				J Med Chem 62: 1609-1625 (2019) Article DOI: 10.1021/acs.jmedchem.8b01868
					More data for this Ligand-Target Pair