BDBM50517446 CHEMBL4582242

SMILES: CSc1nc2ccc(cc2s1)S(=O)(=O)Nc1cccc2cccnc12

InChI Key: InChIKey=VJNLCZZAPNUMEC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glyoxalase I (Homo sapiens (Human))	BDBM50517446 (CHEMBL4582242) Show SMILES CSc1nc2ccc(cc2s1)S(=O)(=O)Nc1cccc2cccnc12 Show InChI InChI=1S/C17H13N3O2S3/c1-23-17-19-13-8-7-12(10-15(13)24-17)25(21,22)20-14-6-2-4-11-5-3-9-18-16(11)14/h2-10,20H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...				J Med Chem 62: 1609-1625 (2019) Article DOI: 10.1021/acs.jmedchem.8b01868
					More data for this Ligand-Target Pair