BDBM50517580 CHEMBL4442134

SMILES: ONC(=O)c1ccc(cc1)N1c2ccccc2Sc2ccccc12

InChI Key: InChIKey=USSSSHLQPDQGMW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517580 (CHEMBL4442134) Show SMILES ONC(=O)c1ccc(cc1)N1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C19H14N2O2S/c22-19(20-23)13-9-11-14(12-10-13)21-15-5-1-3-7-17(15)24-18-8-4-2-6-16(18)21/h1-12,23H,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090
					More data for this Ligand-Target Pair