BDBM50517582 CHEMBL4534310

SMILES: ONC(=O)c1ccc(CCN2c3ccccc3Sc3ccccc23)cc1

InChI Key: InChIKey=DLOYKPSOPLAKIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517582 (CHEMBL4534310) Show SMILES ONC(=O)c1ccc(CCN2c3ccccc3Sc3ccccc23)cc1 Show InChI InChI=1S/C21H18N2O2S/c24-21(22-25)16-11-9-15(10-12-16)13-14-23-17-5-1-3-7-19(17)26-20-8-4-2-6-18(20)23/h1-12,25H,13-14H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090
					More data for this Ligand-Target Pair