BDBM50517817 CHEMBL4446736

SMILES: OC1(COC1)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1

InChI Key: InChIKey=JMLRAWKKJIRKQB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor subfamily 4 group A member 2 (Homo sapiens (Human))	BDBM50517817 (CHEMBL4446736) Show SMILES OC1(COC1)c1cccc(c1)-c1ccc2nc(cn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H17ClN2O2/c23-19-7-4-15(5-8-19)20-12-25-11-17(6-9-21(25)24-20)16-2-1-3-18(10-16)22(26)13-27-14-22/h1-12,26H,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	323	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 29: 929-932 (2019) Article DOI: 10.1016/j.bmcl.2019.01.024
					More data for this Ligand-Target Pair